Arnold Schwarzenegger and Danny DeVito in Twins. (Handout)

Danny DeVito was devastated when Arnold Schwarzenegger launched a career in politics as it cost him millions of dollars by stalling a sequel to their hit comedy TWINS.

The pair teamed up for the 1988 movie, about two long-lost siblings, and DeVito was keen to work on a follow-up 15 years later - but Schwarzenegger torpedoed the proposal as he was running in the election for Governor of California.

DeVito admits the snub sent him into a spiral of despair and he became convinced his pal's political ambitions were "the stupidest thing in the world".

He tells U.K. talk show host Graham Norton, "He became governor of the state of California. I pitched the idea of Twins 2 to him way back then but he told me he was running for the candidacy and I thought that was the stupidest thing in the world.

"I was depressed, not because I thought it was ridiculous and how could this guy run the state, but because I was thinking how much money is this going to cost me if he didn't do the movie. Turns out I was right (about the governorship), it was a disaster!"