Sean 'Diddy' Combs. (AP Files)

Sean 'Diddy' Combs sparked chaos at a New York City nightclub after the MTV Video Music Awards on Sunday as fans flocked to catch a glimpse of the rapper and his A-list pals.

The hip-hop star was celebrating at nightclub 10ak with a host of celebrities, including Justin Timberlake, Rihanna and Lady GaGa, when he and his alleged girlfriend, singer Cassie, decided to leave the afterparty.

A crowd of clubgoers followed the pair onto the street, prompting an undercover cop to ask Diddy to return to the venue in a bid to control the growing mob.

When the rapper refused, patrol cars were forced to shut down the street to ensure the safety of the star and the throng of people, reports the New York Daily News.

A source tells the publication, "It was absolute chaos. People were trying to run past police officers to get a look at who was coming out of the club."

Meanwhile, actresses Jessica Alba and Amanda Bynes also struggled to make a quick exit, and needed several security guards to escort them passed the fans and paparazzi to their waiting cars.

A spokesperson for Diddy has brushed off the incident, insisting, "This was just a minor misunderstanding."